Principal Scientist Job

Company Name:
Salary period: Annual
Senior Scientist/Principal Scientist in Protein Characterization, needed for a direct hire opportunity with Yoh's client located in Cranbury, NJ.
What You'll Be Doing:
- Analytical Support for Process Development, GMP Manufacture, Formulation and Drug Discovery
- Effectively interact with Cell Line Development, Upstream, Downstream, Formulation and Drug Discovery to support biologics development. Ensure timely support.
- Take a lead for conducting routine testing in support of antibody/protein glycosylation characterization (N-glycans, monosaccharaides, sialic acid), primary structure characterization (amino acid sequence coverage analysis, molecular weight determination, amino acid composition analysis, cysteine conformation, free thiol content) and post translational modifications characterization.
- Responsible for method development of carbohydrates analysis, glycation, acidic/basic species of charge isoforms identification and mass spec new methods.
- Responsible for assay qualification, validation and assay transfer/training.
- Take a lead for troubleshooting of analytical issuers.
- Provide training to juror scientists.
- Maintain accurate and timely data records and documentation. Writes SOPs and updates and keeps them current.
- Work with CRO for biophysical characterization.
- Write publication of scientific work.
What You Need to Bring to the Table:
- A BS/MS degree with a minimum of 10 years
- or a PHD degree five (5) years hands-on experience in antibody/protein analyses with various liquid chromatography, liquid chromatography-mass spectrometry methods and biophysical characterization.
- Proven track record supporting biologics drug development
- Solid experience with functional and potency assay development, validation, and tech transfer
- Strong scientific understanding and experience with ELISA, flow cytometry, Biacore/surface plasmon resonance, cell signal transduction, reporter constructs, molecular biology, FACS, and mammalian cell culture. Experience with comparability studies and regulatory filings preferred.
- Motivation to be part of a high performance, efficient scientific team
- Excellent spoken and written communication skills
- The Senior Scientist must have strong interpersonal skills and the desire to work in a high pace biotech environment.
Bonus Points! Otherwise Known As Preferred Qualifications:
- Large Molecule and Protein Experience
What's In It For You?
- This is your chance to shine while supporting our client's dynamic Product Marketing, drug development and Research teams.
Get Hired, Apply Now!
Recruiter: Sidra Chaudhry
Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer, M/F/D/V. Click here to contact us if you are an individual with a disability and require accommodation in the application process.

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